相关神经回路的功能改变是在一定时期的药物成瘾中发生的。这些重大变化也通过分析fMRI揭示。然而，由于fMRI的高维度和信噪比差，因此对于图形识别和尼古丁成瘾（NA）和健康控制之间的图形识别和区域级生物标志物检测任务编码有效且健壮的大脑区域嵌入是一项挑战。 HC）组。在这项工作中，我们将大鼠脑的fMRI表示为具有生物学属性的图形，并提出了一种新型特征选择的图形空间注意网络（FGSAN），以提取成瘾的生物标志物并从这些大脑网络中识别。特别是，使用图形空间注意编码器来捕获具有空间信息的时空脑网络的特征。该方法同时采用贝叶斯特征选择策略，以通过约束功能来优化模型并改善分类任务。与成瘾相关的神经成像数据集进行的实验表明，所提出的模型可以获得卓越的性能并检测与成瘾的神经回路相关的可解释的生物标志物。

不同类型的神经影像数据的跨模式融合显示了预测阿尔茨海默氏病（AD）进展的巨大希望。但是，在神经成像中应用的大多数现有方法无法有效地融合来自多模式神经图像的功能和结构信息。在这项工作中，提出了一种新型的跨模式变压器生成对抗网络（CT-GAN），以融合包含在静止状态功能磁共振成像（RS-FMRI）中的功能信息（RS-FMRI），并包含在扩散张量图像（DTI）中包含的结构信息。开发的双重注意机制可以有效地匹配功能信息，并最大程度地提高从RS-FMRI和DTI提取互补信息的能力。通过捕获结构特征和功能特征之间的深层互补信息，提出的CT-GAN可以检测到与AD相关的大脑连接性，可以用作AD的生物标志物。实验结果表明，所提出的模型不仅可以改善分类性能，而且还可以有效地检测与广告相关的大脑连接性。

Blind image quality assessment (BIQA) remains challenging due to the diversity of distortion and image content variation, which complicate the distortion patterns crossing different scales and aggravate the difficulty of the regression problem for BIQA. However, existing BIQA methods often fail to consider multi-scale distortion patterns and image content, and little research has been done on learning strategies to make the regression model produce better performance. In this paper, we propose a simple yet effective Progressive Multi-Task Image Quality Assessment (PMT-IQA) model, which contains a multi-scale feature extraction module (MS) and a progressive multi-task learning module (PMT), to help the model learn complex distortion patterns and better optimize the regression issue to align with the law of human learning process from easy to hard. To verify the effectiveness of the proposed PMT-IQA model, we conduct experiments on four widely used public datasets, and the experimental results indicate that the performance of PMT-IQA is superior to the comparison approaches, and both MS and PMT modules improve the model's performance.

In this paper, we study the problem of knowledge-intensive text-to-SQL, in which domain knowledge is necessary to parse expert questions into SQL queries over domain-specific tables. We formalize this scenario by building a new Chinese benchmark KnowSQL consisting of domain-specific questions covering various domains. We then address this problem by presenting formulaic knowledge, rather than by annotating additional data examples. More concretely, we construct a formulaic knowledge bank as a domain knowledge base and propose a framework (ReGrouP) to leverage this formulaic knowledge during parsing. Experiments using ReGrouP demonstrate a significant 28.2% improvement overall on KnowSQL.

Temporal sentence grounding (TSG) aims to identify the temporal boundary of a specific segment from an untrimmed video by a sentence query. All existing works first utilize a sparse sampling strategy to extract a fixed number of video frames and then conduct multi-modal interactions with query sentence for reasoning. However, we argue that these methods have overlooked two indispensable issues: 1) Boundary-bias: The annotated target segment generally refers to two specific frames as corresponding start and end timestamps. The video downsampling process may lose these two frames and take the adjacent irrelevant frames as new boundaries. 2) Reasoning-bias: Such incorrect new boundary frames also lead to the reasoning bias during frame-query interaction, reducing the generalization ability of model. To alleviate above limitations, in this paper, we propose a novel Siamese Sampling and Reasoning Network (SSRN) for TSG, which introduces a siamese sampling mechanism to generate additional contextual frames to enrich and refine the new boundaries. Specifically, a reasoning strategy is developed to learn the inter-relationship among these frames and generate soft labels on boundaries for more accurate frame-query reasoning. Such mechanism is also able to supplement the absent consecutive visual semantics to the sampled sparse frames for fine-grained activity understanding. Extensive experiments demonstrate the effectiveness of SSRN on three challenging datasets.

We introduce Argoverse 2 (AV2) - a collection of three datasets for perception and forecasting research in the self-driving domain. The annotated Sensor Dataset contains 1,000 sequences of multimodal data, encompassing high-resolution imagery from seven ring cameras, and two stereo cameras in addition to lidar point clouds, and 6-DOF map-aligned pose. Sequences contain 3D cuboid annotations for 26 object categories, all of which are sufficiently-sampled to support training and evaluation of 3D perception models. The Lidar Dataset contains 20,000 sequences of unlabeled lidar point clouds and map-aligned pose. This dataset is the largest ever collection of lidar sensor data and supports self-supervised learning and the emerging task of point cloud forecasting. Finally, the Motion Forecasting Dataset contains 250,000 scenarios mined for interesting and challenging interactions between the autonomous vehicle and other actors in each local scene. Models are tasked with the prediction of future motion for "scored actors" in each scenario and are provided with track histories that capture object location, heading, velocity, and category. In all three datasets, each scenario contains its own HD Map with 3D lane and crosswalk geometry - sourced from data captured in six distinct cities. We believe these datasets will support new and existing machine learning research problems in ways that existing datasets do not. All datasets are released under the CC BY-NC-SA 4.0 license.

This paper studies the quantization of heavy-tailed data in some fundamental statistical estimation problems, where the underlying distributions have bounded moments of some order. We propose to truncate and properly dither the data prior to a uniform quantization. Our major standpoint is that (near) minimax rates of estimation error are achievable merely from the quantized data produced by the proposed scheme. In particular, concrete results are worked out for covariance estimation, compressed sensing, and matrix completion, all agreeing that the quantization only slightly worsens the multiplicative factor. Besides, we study compressed sensing where both covariate (i.e., sensing vector) and response are quantized. Under covariate quantization, although our recovery program is non-convex because the covariance matrix estimator lacks positive semi-definiteness, all local minimizers are proved to enjoy near optimal error bound. Moreover, by the concentration inequality of product process and covering argument, we establish near minimax uniform recovery guarantee for quantized compressed sensing with heavy-tailed noise.

As an important variant of entity alignment (EA), multi-modal entity alignment (MMEA) aims to discover identical entities across different knowledge graphs (KGs) with multiple modalities like images. However, current MMEA algorithms all adopt KG-level modality fusion strategies but ignore modality differences among individual entities, hurting the robustness to potential noise involved in modalities (e.g., unidentifiable images and relations). In this paper we present MEAformer, a multi-modal entity alignment transformer approach for meta modality hybrid, to dynamically predict the mutual correlation coefficients among modalities for instance-level feature fusion. A modal-aware hard entity replay strategy is also proposed for addressing vague entity details. Extensive experimental results show that our model not only achieves SOTA performance on multiple training scenarios including supervised, unsupervised, iterative, and low resource, but also has limited parameters, optimistic speed, and good interpretability. Our code will be available soon.

Deep learning has been widely used for protein engineering. However, it is limited by the lack of sufficient experimental data to train an accurate model for predicting the functional fitness of high-order mutants. Here, we develop SESNet, a supervised deep-learning model to predict the fitness for protein mutants by leveraging both sequence and structure information, and exploiting attention mechanism. Our model integrates local evolutionary context from homologous sequences, the global evolutionary context encoding rich semantic from the universal protein sequence space and the structure information accounting for the microenvironment around each residue in a protein. We show that SESNet outperforms state-of-the-art models for predicting the sequence-function relationship on 26 deep mutational scanning datasets. More importantly, we propose a data augmentation strategy by leveraging the data from unsupervised models to pre-train our model. After that, our model can achieve strikingly high accuracy in prediction of the fitness of protein mutants, especially for the higher order variants (> 4 mutation sites), when finetuned by using only a small number of experimental mutation data (<50). The strategy proposed is of great practical value as the required experimental effort, i.e., producing a few tens of experimental mutation data on a given protein, is generally affordable by an ordinary biochemical group and can be applied on almost any protein.

Pure transformers have shown great potential for vision tasks recently. However, their accuracy in small or medium datasets is not satisfactory. Although some existing methods introduce a CNN as a teacher to guide the training process by distillation, the gap between teacher and student networks would lead to sub-optimal performance. In this work, we propose a new One-shot Vision transformer search framework with Online distillation, namely OVO. OVO samples sub-nets for both teacher and student networks for better distillation results. Benefiting from the online distillation, thousands of subnets in the supernet are well-trained without extra finetuning or retraining. In experiments, OVO-Ti achieves 73.32% top-1 accuracy on ImageNet and 75.2% on CIFAR-100, respectively.